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Prof. Dr. med. Dragos Inta MD

Affiliated group leader

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Researchgate profile

Professor Inta heads the Molecular Psychiatry research team. He is clinical psychiatrist and neuroscientist, graduate from the University of Heidelberg and trained in psychiatric practice at the Central Institute of Mental Health in Mannheim. He is appointed associated Professor of Psychiatry at the University of Heidelberg. His Research interests include neurobiological mechanisms of psychiatric disorders, especially schizophrenia and affective disorders, as well as developmental neuroscience and psychopharmacological topics.

Projects

Speaker: ERA-NET NEURON (EU-Horizon 2020) „Synaptic Dysfunction in Disorders of the Central Nervous System“ „Understanding symptoms induced by NMDA receptor dysfunction: from mechanisms to prevention and therapy (NMDAR-PSY)“

Ingeborg-Ständer-Foundation „Deciphering the role of glutamatergic mechanisms in inhibitory versus excitatory Neurons in inducible pharmatogenic mouse models of schizophrenia

Selected publications

Inta D, Alfonso J, von Engelhardt J, Kreuzberg M, Meyer AH, van Hooft JA, Monyer H (2008) Neurogenesis and widespread forebrain migration of distinct GABAergic interneurons from the postnatal subventricular zone. Proc Natl Acad Sci USA, 105:20994-20999.                                            

Chameau P, Inta D, Vitalis T, Monyer H, van Hooft JA (2009) The N-terminus of reelin controls the dendritic arborisation of pyramidal neurons. Proc Natl Acad Sci USA 106:7227-7232.

Inta D, Meyer-Lindenberg A, Gass P (2011) Alterations in Postnatal Neurogenesis and Dopamine Dysregulation in Schizophrenia: A Hypothesis. Schizophr Bull 37:674-680.

Inta D, Filipovic D, Lima-Ojeda JM, Dormann C, Pfeiffer N, Gasparini F, Gass P (2012) The mGluR5 antagonist MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: significance for the use as anxiolytic/antidepressant drug. Neuropharmacology 62:2034-2039.

Inta D, Lima-Ojeda JM, Lau T, Tang W, Sprengel R, Schloss P, Sartorius A, Meyer-Lindenberg A, Gass P (2013). Electroconvulsive therapy induces neurogenesis in frontal rat brain areas. PLoS ONE 8:e69869.                                            

Inta D, Vogt MA, Elkin H, Weber T, Lima-Ojeda JM, Schneider M, Luoni A, Riva MA, Gertz K, Hellmann-Regen J, Kronenberg G, Meyer-Lindenberg A, Sprengel R, Gass P (2014) Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: relevance for mental disorders. Hippocampus 24:424-435.

Inta D, Cameron HA, Gass P (2015) New neurons in the adult striatum: from rodents to humans. Trends Neurosci 38:517-523.

Inta D, Lang UE, Borgwardt S, Meyer-Lindenberg A, Gass P (2016) Adult neurogenesis in the human striatum: possible implications for psychiatric disorders. Mol Psychiatry 21:446-447.